V2EX overexpression

Overexpression

释义 Definition

(尤指生物学/遗传学)过表达:指某个基因或蛋白质在细胞中被产生的量高于正常水平,常见于实验操作(如转染、诱导表达)或疾病状态(如某些癌症)。

发音 Pronunciation

/ovrksprn/

例句 Examples

Overexpression of this gene can slow the growth of the cells.
该基因的过表达会减缓细胞的生长。

The researchers observed that overexpression of the receptor altered signaling pathways, leading to abnormal cell behavior.
研究人员观察到该受体的过表达改变了信号通路,从而导致细胞出现异常行为。

词源 Etymology

**over-**(“过度、超过”)+ expression(“表达”)。这里的 expression 多指生物学中的“基因表达/蛋白表达”,合在一起就是“表达量超过正常水平”。在分子生物学文献中非常常用。

相关词 Related Words

文学与作品 Literary Works

  • 《The Biology of Cancer》(Robert A. Weinberg):讨论癌症相关基因的异常表达与过表达现象。
  • 《Molecular Biology of the Cell》(Alberts 等):在细胞信号与基因调控章节中常用 overexpression 描述实验操控表达水平。
  • 《Nature》《Science》《Cell》 等期刊论文:overexpression 常出现在基因功能研究与疾病机制研究中(多为学术写作语境)。
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